Eerdman's Commentary puts it well stating that in 1 Cor 1:18,19 "Paul contrasts human wisdom, which leaves God out of account and is man-centered, with the wisdom of God."
This explains that human wisdom (a presuppositional approach which denies or fails to acknowledge God) not only will not lead to God, but is inferior to the wisdom of God.
... hence the message of the cross - the means (rather than human wisdom)of salvation.
Not stopping there, the same source goes on to say "...true rightness comes from a broken heart, not from brains."
(Note: Human wisdom also denies or fails to recognize sin, but Christ crucified does! Hence Christ is the power and wisdom of God leading to salvation, not human wisdom.)